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Drug-target interaction, molecular screening, ADMET, compound databases, pharmaceutical data
627 datasets
A method for quantifying glycerol, sorbitol, and sucrose in pharmaceutical formulations using ion chromatography with pulsed amperometric detection. The dataset, authored by Raul Arruda Artisiani and last updated in April 2026, includes validation results demonstrating linearity from 1β100 mg Lβ»ΒΉ, precision with RSD β€ 0.7%, and low detection limits between 3.0β24 Β΅g Lβ»ΒΉ.
Ruguo Ren published a dataset on figshare in April 2026 detailing the multi-target mechanisms of the neutrophil elastase inhibitor Sivelestat in experimental autoimmune myocarditis. The 12.0 KB XLSX file likely contains results from network pharmacology, molecular docking, and in vivo mouse model experiments. Data includes computational target identification, cytokine levels, cardiac function measurements, and pathway analysis from a study with 6 mice per group.
41 potential drug targets were identified through network pharmacology analysis of the neutrophil elastase inhibitor Sivelestat for myocarditis. The dataset includes results from molecular docking and in vivo experiments on male BALB/c mice, with interventions at 50, 100, and 200 mg/kg/day. It was authored by Ruguo Ren and last updated on 2026-04-30.
Experimental data from a study investigating the cardioprotective mechanisms of the neutrophil elastase inhibitor Sivelestat in a mouse model of autoimmune myocarditis. The dataset, shared by Ruguo Ren on figshare under CC-BY-4.0, includes computational network pharmacology results and in vivo experimental measurements from male BALB/c mice treated with Sivelestat. It was last updated on April 30, 2026.
PolygloToxicityPrompts is a multilingual toxicity evaluation benchmark curated from web text. The dataset includes three splits: ptp-full, ptp-small, and wildchat, containing 25,000, 5,000, and 1,000 prompts per language, respectively. It was created by ToxicityPrompts and last updated on 2026-05-29.
Information on pharmaceutical regulatory systems in Asian countries, collected by Ashish Katke and hosted on Harvard Dataverse. The data relates to drug approval processes, clinical trial conduct, and post-market safety monitoring. The dataset was last updated on June 19, 2026.
A K Cho from the University of California, Los Angeles authored this research paper on pharmacokinetic approaches to drug action and toxicity. The paper was published on the paperswithcode platform. Its specific content and data availability require verification after download.
A 315-byte dataset from figshare, last updated in May 2026, describes the preclinical evaluation of two novel AKR1C3-activated Exatecan drug conjugates, EP-1 and EP-2. The data, authored by Ningfang Kang, includes results from in vitro cytotoxicity assays, cellular and zebrafish imaging for drug release tracking, and in vivo mouse model efficacy and toxicity studies. The findings nominate EP-2 as a candidate for selective tumor therapy with reduced systemic toxicity.
A research paper authored by Ted M. Dawson of Johns Hopkins University, published on the paperswithcode platform. The work likely contains data and analysis related to the role of nitric oxide in neurotoxic processes. The specific temporal coverage and dataset size are unknown.
A research document details in silico drug repurposing findings for the antibiotic-resistant pathogen Haemophilus influenzae. The study, authored by Srujal Kacha, reports molecular docking and simulation results for the FDA-approved drug valsartan against wild-type penicillin-binding protein 3 and two common mutants. The document was last updated on April 28, 2026.
A research document details an integrated computational and experimental study on Cervus cucumis polypeptide injection (CCPI) for Alzheimer's disease. The study, authored by Xiaowei Fu and uploaded to figshare in April 2026, identifies 28 active components and 50 common targets, focusing on the IL-6/STAT3/VEGF pathway. It includes results from network pharmacology, molecular docking, molecular dynamics simulation, and in vitro validation on AΞ²-induced microglial cells.
Jun Zhou's research dataset investigates the potential role of gut microbiota metabolites in endometriosis using network pharmacology and Mendelian randomization. The 115.5 MB ZIP file contains results identifying key biomarker genes related to protective gut microbial metabolites. The dataset was last updated on 2026-05-31 and is shared under a CC-BY-4.0 license.
A review document compiling data on ocular toxicity reported during clinical development and postmarketing surveillance for all currently approved antibody-drug conjugates (ADCs). The text analyzes potential mechanisms, summarizes reported adverse events and their incidence, and explores mitigation strategies. It was authored by Junxiang Zhou and last updated on 2026-04-27.
A 2026 review by Junxiang Zhou compiling data on ocular toxicity from all currently approved antibody-drug conjugates (ADCs). The document, shared on figshare under a CC-BY-4.0 license, analyzes reported adverse events, their incidence, and potential mitigation strategies. It is a 17.8 KB DOCX file.
A review document compiling data on ocular toxicity reported during clinical development and postmarketing surveillance of all currently approved antibody-drug conjugates (ADCs). The document analyzes potential mechanisms, summarizes reported ocular adverse events and their incidence, and explores mitigation strategies. It was authored by Junxiang Zhou and last updated on 2026-04-27.
A review document on figshare authored by Xiaoya Li, last updated on 2026-04-21. The 24.4 KB document systematically evaluates the Erzhi Pill, a traditional Chinese medicine formula used for nearly six centuries, covering its constituent botanical drugs, phytochemical profiles, efficacy, mechanisms, and applications.
A 112.8 KB review document authored by Xiaoya Li and last updated on 2026-04-21. It systematically evaluates the Erzhi Pill, a traditional Chinese medicine formula used for nearly six centuries, covering its constituent botanical drugs, phytochemical profiles, efficacy, mechanisms, and applications. The document is shared under a CC-BY-4.0 license on figshare.
A review document authored by Xiaoya Li, last updated on April 21, 2026, and shared on figshare under a CC-BY-4.0 license. The 93.1 KB file systematically evaluates the Erzhi Pill, a traditional Chinese medicine formula used for nearly six centuries, covering its constituent botanical drugs, phytochemical profiles, efficacy, mechanisms, and applications.
A review document systematically evaluates the Erzhi Pill, a traditional Chinese medicine formula used for nearly six centuries. The review covers the resource distribution, phytochemical profiles, efficacy, mechanisms, and applications of its constituent botanical drugs. It was authored by Xiaoya Li and last updated on 2026-04-21.
Yang Liu published a dataset on figshare in April 2026 detailing the discovery of benzoselenazinone compounds as DprE1 inhibitors for tuberculosis treatment. The dataset likely contains tabular data on compound derivatives, including measurements of anti-TB activity (MIC), cytotoxicity (Vero IC50), and DprE1 inhibition (IC50). It also includes pharmacokinetic properties such as oral bioavailability for a lead compound.