Loading...
Loading...
DNA/RNA sequences, gene expression, protein structures, metagenomics, single-cell sequencing
27,749 datasets
Cryoelectron microscopy structures of the full native virion and an uncoating intermediate of Enterovirus D68, determined at 2.2- and 2.7-Å resolution, respectively. The data, produced by researchers at Purdue University West Lafayette, delineates the pathway of EV-D68 uncoating and provides the molecular basis for its acid lability.
Five human subjects provided peripheral blood for eosinophil isolation. Purified cells were incubated for 4 hours, then exposed to dexamethasone or vehicle for 30, 60, or 120 minutes before RNA extraction and qPCR analysis for 11 target genes. The dataset presents mean Ct values for each subject, condition, and time point, calculated from two technical replicates per sample.
A 1.8 Å resolution X-ray structure of the anthraquinone derivative AQS2 bound to the DNA duplex (d(CGTACG))2, showing an intercalated, groove-reversed complex. The dataset, from Susan M. Gasper of the Georgia Institute of Technology, details guanine-AQS2 interactions and molecular orbital overlap, supporting a model for electron transfer after photoexcitation. The structure reveals two AQS2 molecules intercalated at each CG step, with the out-of-plane swallow tail located in the major groove.
Sophie Anne Inès Klopfenstein from Humboldt-Universität zu Berlin created this dataset of structured mappings for annotating and analyzing alarms in intensive care units. The mappings, which do not include patient data, are based on information from patient data management systems, clinical expertise, and standards like ISO 19223:2019. They cover respiratory support therapies, airway devices, ventilation modes, and medication interventions linked to physiological alarm conditions.
A research dataset from Wannan Medical College investigates the role of the FTO protein in STAT3-mediated doxorubicin resistance in breast cancer. The study includes data from experiments such as CHIP assays and dual luciferase reporter assays performed on doxorubicin-resistant and standard breast cancer cell lines. The dataset is associated with an open-access research paper.
A study by Tianyi Gao of the University of Bristol investigated the role of long non-coding RNA 91H in colorectal cancer. The research detected higher expression of lncRNA 91H in CRC tissues and cells compared to normal ones, and found a significant interaction between lncRNA 91H and the protein IGF2BP2. These results suggest a mechanism for promoting IGF2 expression, indicating potential diagnostic and therapeutic targets.
Six point clouds show the internal geometry of pits on the Moon. The data was generated via manual feature matching in oblique stereo pairs of Lunar Reconnaissance Orbiter Narrow Angle Camera images. R. V. Wagner of Arizona State University created this archive, with methods detailed in Wagner and Robinson (2022).
Antarctic all-sky imager observations from the Chinese Zhongshan Station on April 23rd, 2019. The dataset contains image files in PNG format, with each compressed file corresponding to a specific observed waveband, namely 5577 Å and 6300 Å. The data was contributed by Xingyu Li from Peking University and is available under an Open Access license.
Supplementary data for the OMArk paper includes simulated proteomes with errors, UniProt Reference Proteomes from 2021, and Ensembl Metazoa proteomes from versions 52 and 54. The dataset was created by Yannis Nevers at the University of Lausanne and contains archives for OMAmer databases, OMArk results, and BUSCO assessments. It supports the evaluation of the OMArk tool for assessing the completeness and contamination of proteome annotations.
Combined transcriptome and metabolome data from two pepper genotypes with differing susceptibility to spider-mite infestation. The data was generated by researchers at Wageningen University & Research to study jasmonic acid and salicylic acid signaling pathways in plant defense. Analysis suggests the more resistant genotype exhibited a larger increase in endogenous JA and secondary metabolites upon infestation.
A study evaluating the influence of test parameters on the tensile bond strength of mortar renderings. The research combined a Finite Element Method computer model with laboratory experiments on 530 specimens applied to concrete slabs. It was conducted by Eliane Betânia Carvalho Costa at Universidade de São Paulo.
Erika Alves dos Santos from Universidade de São Paulo compiled raw and aggregated bibliographic data for a study on citation and referencing habits. The dataset is based on 729 articles from 147 journals across 27 subject areas, containing 34,140 bibliographic references and 55,100 mentions and quotations. It includes raw discipline-specific files, aggregated summary data, a metadata subset, and journal selection information.
Replication package for a paper presented at ICSE '21 on how showing code metrics influences understanding. The data folder contains the dataset, R analysis script, and figures needed to reproduce the study's statistical analysis. Authors from the University of Stuttgart removed potentially identifying fields like age and gender for privacy, but state the dataset still allows full reproducibility.
Dandan Zou from Harbin Medical University analyzed RNA sequencing data from The Cancer Genome Atlas (TCGA) for soft tissue sarcoma patients. The study identified 328 differentially expressed mRNAs, 18 miRNAs, and 67 lncRNAs, constructing a competing endogenous RNA (ceRNA) network and protein-protein interaction network. It validated the expression of five specific mRNAs (APOL1, EFEMP1, LYZ, RARRES1, TNFAIP2) and identified several biomarkers associated with patient survival.
A transcriptome of the arrow worm Spadella cephaloptera was searched for photoreceptor-related genes. The screen revealed two xenopsin copies, one peropsin copy, and one cryptochrome gene, with expression patterns analyzed in developing and adult eyes. The dataset was generated by Tim Wollesen of the University of Vienna to study eye development in Gnathifera.
Multisurface adiabatic reactive molecular dynamics simulations reveal a competition between concerted and stepwise pathways for the polar cycloaddition of 2,3-dibromobutadiene radical ions with maleic anhydride. Uxía Rivero from the University of Basel conducted the study, which computed reaction rates of k=5.1×10⁻¹⁴ s⁻¹ for the s-cis and k=3.8×10⁻¹⁴ s⁻¹ for the s-trans conformer at 300 K. The results are intended to inform experimental studies of polar cycloadditions under single-collision gas-phase conditions.
High-throughput sequencing data from Daphnia magna investigates the rate of loss of heterozygosity during asexual reproduction. Marinela Dukić from the University of Basel used Restriction site Associated DNA sequencing to compare parthenogenetic daughters with their mothers at several thousand genetic markers. The study concluded that LOH does not occur frequently in D. magna, suggesting clonal lineages remain genetically homogeneous over typical experimental timeframes.
An R package developed by Rebecca Barter at the University of California, Berkeley, for visualizing complex datasets. The package provides a flexible and customizable platform for creating heatmaps that can be extended with scatterplots, boxplots, and barplots. Its capabilities are demonstrated through three reproducible case studies using publicly available data.
Gargeda State Forest in western Ethiopia is the focus of a study assessing Participatory Forest Management. The research, conducted by Zelalem Telila, used surveys, interviews, and document reviews to evaluate governance performance, socio-economic outcomes, and barriers among Forest User Groups. Results include community awareness at 85%, women's participation at 15.6%, and willingness for conservation training at 83%.
Pascal Mohamed Mounchid's dataset examines child marriage rates in India and Zambia during the COVID-19 pandemic. It contains quantitative and qualitative data collected from 3,049 adolescent girls aged 13–18 in India and 1,615 aged 15–19 in Zambia between February and September 2022. The analysis focuses on socio-cultural and economic influences, including dowry and bride price practices.