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DNA/RNA sequences, gene expression, protein structures, metagenomics, single-cell sequencing
23,852 datasets
An umbrella review re-analyzes 18 systematic reviews on maternal probiotic supplementation and offspring health. The analysis encompasses 62 specific offspring-related outcomes, with summary effects re-estimated using random-effects models. The dataset presents findings on outcomes like eczema risk and breast milk microbiota, graded for evidence certainty and credibility.
Bin Liu from Shanghai Jiao Tong University proposes a role for the COL13 gene in hypocotyl elongation in Arabidopsis thaliana. The research demonstrates that COL13 RNA accumulates in hypocotyls and its disruption leads to longer hypocotyls in red light, while overexpression results in shorter hypocotyls. The study identifies a HY5-COL3-COL13 regulatory chain and a possible COP1-dependent feedback pathway for mediating hypocotyl elongation.
Yuepeng Song from Beijing Forestry University identified 261 high temperature-responsive long noncoding RNAs (lncRNAs) in poplar (Populus simonii). These lncRNAs were predicted to target 353 genes, with 163 cis-targets and 190 trans-targets. The study includes experimental validation of lncRNA function through overexpression and repression assays in poplar leaves and roots.
Smithsonian scientists use genomics to address conservation challenges like disease detection and species identification. Their work involves DNA from non-invasive sources like feces, hair, and museum specimens. The data likely supports projects on population genetics, paternity testing, and evolutionary history.
Tatsuhiko Hoshino from the Japan Agency for Marine-Earth Science and Technology applied quantitative sequencing (qSeq) to environmental DNA (eDNA) analysis. The dataset likely contains quantitative eDNA measurements for five fish species (Hemigrammocypris neglectus, Candidia temminckii, Oryzias latipes, Rhinogobius flumineus, and Misgurnus anguillicaudatus) sampled from aquaria across four days. The study validated qSeq results against digital PCR measurements, finding correlation coefficients of 1.052, 1.074, and 1.114 for three of the species.
Jiangsu Normal University research provides RNA-seq data on tomato plants with altered SlSTE1 gene expression under salt stress. The dataset likely contains differential gene expression data for 1330 genes identified between overexpression and wild-type plants. It was authored by Xiaoqing Meng and is available via paperswithcode.
A dataset from a research paper describing a strategy for creating hybrid superamphiphobic coatings. The data likely contains experimental results related to coating adhesion, mechanical deformation, and recyclability. The work was authored by Zhenqiang Zhang from Guangzhou University.
A study characterizing the T. hispida MYB (ThMYB8) transcription factor during salt stress using transgenic assays. Research from Northeast Forestry University demonstrates ThMYB8 overexpression enhances tolerance by regulating downstream genes and physiological parameters. The dataset likely contains gene expression and physiological measurement data from transgenic T. hispida and Arabidopsis plants.
The Tabernas-Sorbas Basin in Almeria, Spain, provides a case study on desertification misconceptions. The dataset likely contains information on olive agriculture expansion, irrigation changes, and aquifer water balance impacts from 1970 to the present. It was authored by Jaime Martínez‐Valderrama of the University of Alicante.
Edoardo Errichiello from the University of Pavia published a study characterizing a novel loss-of-function variant in the TDP2 gene. The dataset likely contains clinical and functional assay data from two adult Italian siblings with spinocerebellar ataxia autosomal recessive 23 (SCAR23). Findings support the pathogenic role of biallelic TDP2 variants and detail the adult clinical phenotype.
A dataset from a study by Alice Dore at the University of East Anglia examines the fitness consequences of redundant sensory cues in male fruit flies. The research exposed male Drosophila melanogaster to alternative combinations of rival cues (sound, smell, touch) and measured subsequent mating duration and reproductive success under sperm competition. Results showed behavioral redundancy in response to cues but no identifiable fitness benefits from longer mating durations under the tested conditions.
A genomic analysis study identified 44 core genes across 32 ranavirus genome sequences. The research, conducted by Wenjie Zhang from Zunyi Medical University, constructed multiple phylogenetic trees to explore ranavirus taxonomy. It concluded by selecting four genes suitable for convenient and accurate taxonomic identification.
Manibarathi Vaithiyanathan from the Louisiana State University System investigated the cellular internalization of unstructured D-chirality cell penetrating peptides (CPPs). The work reports a three-fold increase in uptake and a 50-fold increase in stability for D-chirality peptides compared to L-chirality counterparts. Findings highlight a new exocytosis-independent expulsion pathway and the peptides' potential as bio-vectors.
The National Human Genome Research Institute's Ethical, Legal and Social Implications Research Program hosts a question-and-answer session on genomics. Experts from the NHGRI address societal impacts of genomic data, covering topics from forensics and ancestry to precision medicine and CRISPR. The session is intended to explore ethical considerations in genomic research and clinical application.
Genomic evidence for gene flow between monarchs with divergent migratory phenotypes and flight performance is a dataset from a study by Venkat Talla of Emory University. It includes over 20 million SNPs from 43 monarch genomes and tethered flight mill performance data. The research investigates genomic differentiation between eastern and western North American monarch populations.
Joseph E. Neigel from the University of Louisiana at Lafayette investigated genetic population structure in blue crabs (Callinectes sapidus). The dataset comprises genotypes for 1446 individuals sampled from 2010 to 2016 at 2486 SNPs across 1363 putative protein-coding loci. Sampling was most intensive in five Louisiana estuaries, with collections of megalopae, juveniles, and adults.
A proteomics study of maize (Zea mays L.) seedlings under drought conditions, authored by Hamada AbdElgawad of the University of Antwerp. The research identified 284 differentially expressed proteins related to photosynthesis, metabolism, and redox-regulation. It functionally characterized starch biosynthesis using a mutant strain to demonstrate its role in maintaining growth and recovery.
A study by Max Mowbray at the University of Manchester explores the application of Gradient Boosting for dynamic modelling and prediction in bioprocesses. The work includes case studies on fermentation and algal photo-production processes, comparing the data efficiency of Gradient Boosting against artificial neural networks. It concludes that Gradient Boosting may offer advantages for predictive modelling with small experimental datasets.
A study exploring the effect of puerarin on skeletal muscle atrophy in rats with streptozotocin-induced type 1 diabetes. The dataset likely contains measurements of muscle weight, size, strength, fiber type transformation, and gene expression markers from in vivo and in vitro experiments. It was authored by Lin Yin from the Chinese Academy of Medical Sciences & Peking Union Medical College and shared via Papers with Code.
Transcriptomic data compares postharvest peach fruits stored under common and high temperature conditions. The dataset was created by Xiao Wang at Huazhong Agricultural University and is available via paperswithcode. It includes measurements of ethylene production, pulp softening, and gene expression levels for enzymes and transcription factors.