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Medical imaging (X-ray, CT, MRI), electronic health records, clinical trials, ECG/EEG, pathology
14,877 datasets
This dataset originates from an experimental study investigating fatigue crack growth from cold-expanded holes. The research utilized thermoelastic stress analysis (TSA) and synchrotron x-ray diffraction (SXRD) to measure crack growth rates, crack tip plastic zones, and residual stress distributions. It was authored by Khurram Amjad and published in 2020.
489 high-resolution microCT scans from 431 specimens represent 53 primate species, forming the largest high-fidelity comparative dataset of its kind. The data were collected at Harvard's Center for Nanoscale Systems to study primate skull morphology and are archived on MorphoSource.org. Physical specimens are vouchered at Harvard's Museum of Comparative Zoology.
Prospective diffusion-weighted imaging data from 9 non-small cell lung cancer patients with 13 total lesions. Imaging was performed before and at three time points after chemotherapy initiation to evaluate functional diffusion maps (fDMs) as a biomarker for treatment response. The study analyzed changes in apparent diffusion coefficient (ADC) values and the percentage of voxels with significantly increased or decreased ADCs.
Sixty-four patients with primary progressive aphasia were evaluated at baseline, with a subset of 39 assessed longitudinally. The dataset contains quantitative articulation rate measurements from spontaneous speech and baseline MRI-derived cortical thickness data to investigate motor speech impairment and its neuroanatomical basis.
143 consecutive Parkinson's disease patients were assessed for motor and cognitive symptoms before and up to 10 years after subthalamic nucleus deep brain stimulation (STN-DBS) surgery. The dataset tracks symptom progression, treatment efficacy attenuation, and mortality, with a median observation time of 12 years after surgery. Axial disability level was the only symptom significantly predicting death, with a hazard ratio of 4.30 per unit increase.
This dataset supports a new method for designing radiofrequency (RF) pulses using numerical optimization in the wavelet domain for magnetic resonance imaging. It includes data from simulations and human brain imaging to demonstrate optimized slice profiles and reduced peak RF power for simultaneous multi-slice diffusion acquisitions. The dataset was authored by Andrew M. Huettner and last updated in June 2020.
Apit Hemakom's dataset quantifies team cooperation through physiological synchrony measures. It contains respiratory and heart rate variability signals from professional choir singers and surgical teams. The data supports the evaluation of intrinsic synchrosqueezing and nested intrinsic phase synchrony algorithms.
Encompassing multimodal structural neuroimaging data from 30 unmedicated patients with obsessive-compulsive disorder (OCD) and 34 healthy controls. It was created by Seung-Goo Kim and published in 2020, applying the mCCA+jICA fusion method to T1-weighted MRI and diffusion tensor imaging (DTI) data. The analysis identified six highly correlated multimodal networks with significant alterations in gray and white matter.
2020 research data characterizes FOXP3+ regulatory T cells (Tregs) and FOXP3- CD4+ T cells from intestinal lamina propria and blood samples of patients with and without inflammatory bowel disease (IBD). The dataset includes immunophenotyping results for markers such as Helios, CD39, CTLA4, and PD-1, comparing expression levels between cell populations and patient groups. It was authored by James D. Lord and published under a CC0 license.
20 female patients with primary biliary cholangitis (PBC) and 20 female age-matched controls were examined for fatigue, psychological symptoms, and cognitive performance. The dataset includes results from clinical questionnaires, established cognition tests, a computerized attention battery, and 3 Tesla MRI scans analyzed with voxel-based morphometry and diffusion tensor imaging. It was created by Roman Zenouzi and last updated in June 2020.
Dryad hosts qualitative interview data from a study of 20 UK General Practitioners across 16 South London practices. The research explores GPs' views on headache management and their use of direct-access MRI scans. It includes outcomes from an educational session on headache medication, diagnosis, and management.
This dataset contains paleopathological evidence from a Middle Triassic eosauropterygian reptile, suggesting a tuberculosis-like respiratory infection. It is based on high-resolution X-ray microtomography and histological studies of pathologically altered ribs and vertebrae, authored by Dawid Surmik and published in 2020. The specific row and column counts are not provided.
This dataset contains electrocardiogram (ECG) measurements recorded from head and in-ear locations to validate a biophysics model for cardiac signal propagation. The data enables reliable identification of the P-, Q-, R-, S-, and T-waves within the cardiac cycle. It was authored by Wilhelm Christopher von Rosenberg and published in June 2020.
Experimental data from a study investigating COPD-like pathology in polymeric immunoglobulin receptor-deficient (pIgR−/−) mice. The dataset captures associations between SigA deficiency, altered lung microbiome, bacterial invasion, and progressive airway remodeling. It was authored by Bradley W. Richmond and last updated in June 2020.
Encompassing a scaled 3D model of an adult quail's ear created from micro-CT images, aligned with 17 annotated histological sections. It was created by Anna Bonsmann and published in 2020 to serve as an anatomical reference and educational tool.
Featuring computational model results comparing central artery biomechanics in adult wild-type and fibulin-5 deficient mice, a model of early vascular ageing. Findings are examined as a function of sex, with models informed by micro-computed tomography imaging and in vivo ultrasound and pressure measurements.
Data from a study evaluating the Bruton's Tyrosine Kinase and IL-2 Inducible T-cell Kinase inhibitor ibrutinib for preventing chronic graft-versus-host disease (cGVHD). The research tested ibrutinib across four different mouse models, finding it significantly alleviated cGVHD and increased long-term survival. The dataset includes measurements of clinical scores, serum autoantibodies, costimulatory molecule activation, B-cell proliferation, and glomerulonephritis.
Leonard H van den Berg and a committee of 140 international ALS experts published revised consensus guidelines in 2020. The dataset contains 112 recommendations across nine research areas, with 15 prioritized as having the greatest potential for impact. It was developed using a modified Delphi process following a face-to-face workshop.
2060 patients from 11 randomized controlled trials compare anti-VEGF agents and corticosteroids for macular edema secondary to central retinal vein occlusion. The data supports network meta-analysis of therapeutic effects on best-corrected visual acuity and central retinal thickness, and safety outcomes including intraocular pressure and cataracts. Results rank treatments like aflibercept and ranibizumab based on simulation.
Experimental data from a study correlating electrical transmural impedance with histological inflammation in a rat model of inflammatory bowel disease. The research used four platinum ball electrodes placed in the rat small intestine to measure impedance changes over a 3-hour testing period following TNBS injection. The dataset supports the development of a real-time, quantitative diagnostic method for mucosal barrier function.