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DNA/RNA sequences, gene expression, protein structures, metagenomics, single-cell sequencing
23,808 datasets
155 chemical constituents of the Traditional Chinese Medicine formula Bushen Huoxue Recipe were identified for treating recurrent spontaneous abortion. Transcriptome sequencing and network pharmacology analysis identified 267 therapeutic targets, with experimental validation showing reduced embryonic loss in a mouse model. The dataset, shared under a CC-BY-4.0 license, contains results linking the formula's efficacy to the PI3K/AKT signaling pathway.
A research document details a study on the molecular mechanisms of Bushen Huoxue Recipe (BSHXR) for treating recurrent spontaneous abortion (RSA). The work includes UPLC–Q–TOF–MS/MS analysis identifying 155 chemical constituents, transcriptome sequencing, network pharmacology identifying 267 therapeutic targets, and in vivo mouse model experiments. The dataset was authored by Jingheng You and uploaded to figshare on 2026-04-21.
155 chemical constituents of the Traditional Chinese Medicine formula Bushen Huoxue Recipe were identified via UPLC–Q–TOF–MS/MS. The dataset includes transcriptome sequencing and network pharmacology results linking the formula to 267 therapeutic targets and the PI3K/AKT pathway, supported by mouse miscarriage model data. Authored by Jingheng You and last updated on 2026-04-21, this 41.9 KB document is shared under a CC-BY-4.0 license on figshare.
155 chemical constituents of Bushen Huoxue Recipe were identified alongside 267 therapeutic targets for recurrent spontaneous abortion. Transcriptome sequencing and network pharmacology analyses suggest the PI3K/AKT pathway is a key mechanism for intervention. The dataset, authored by Jingheng You and last updated in April 2026, includes results from a mouse miscarriage model.
A 4.1 MB DOCX file contains genomic and phenotypic analysis of a single methicillin-susceptible Staphylococcus aureus (MSSA) ST398 isolate from a household in Vienna, Austria. The analysis includes antimicrobial susceptibility testing, disinfectant susceptibility testing, and whole-genome sequencing results compared to 273 other MSSA ST398 strains. The dataset was authored by Adrienn Gréta Tóth and last updated on April 21, 2026.
322.9 KB of data and code supporting a 2026 methodological paper by Yanxi Hu on multivariate equivalence and component-wise superiority tests for paired samples. The dataset includes R code and a DOCX document illustrating the proposed Intersection-Union Test and Likelihood Ratio Bootstrap Tests. Simulation studies demonstrate the method's ability to control type I error rates.
A 957.8 KB research document authored by Minhao Zhang and last updated in April 2026 details findings on the circular RNA circPVT1 in renal cell carcinoma. The study analyzes circPVT1 expression, its correlation with poor prognosis, and its role in promoting epithelial-mesenchymal transition and macrophage polarization. It includes results from single-cell sequencing, ELISA assays measuring IL-4, IL-10, and TGF-β secretion, and tests of a nanotherapeutic inhibitor system.
Additional file 4 provides a comparative analysis of genome statistics for the citrus-parasitic nematode Tylenchulus semipenetrans. The dataset, authored by Hongjing Huang and shared under a CC-BY-4.0 license, compares T. semipenetrans with five plant-parasitic nematodes, C. elegans, and two animal-parasitic nematodes. It was last updated on May 12, 2026.
Hongjing Huang published an annotated KEGG pathway table for the complete genome of Tylenchulus semipenetrans, a nematode causing citrus slow decline disease. The dataset is available as a 75.5 KB Excel file under a CC-BY-4.0 license. It was last updated on May 12, 2026.
Exome sequencing data from a single clinical case links biallelic DNAAF1 variants to primary ciliary dyskinesia and male infertility. The 11.7 KB dataset, uploaded by Baoqiong Liao to figshare, includes a newly identified missense variant (c.524T>C) and a previously reported nonsense variant (c.1462C>T). Bioinformatic predictions and segregation analysis support the pathogenic potential of these variants, which are implicated in impaired dynein arm assembly and ciliary motility.
5.5 KB of normalized Bru-seq read counts for nascent ELAVL4 and PABPC4L transcripts. The data, authored by Derek Daigle and published in 2020, captures two replicates from HH514-16 cells exposed to sodium butyrate for 3, 24, and 48 hours to study lytic cycle reactivation.
A 1.0 MB dataset from figshare documents the effects of γ-Aminobutyric acid (GABA) on bovine skeletal muscle satellite cells. The data, authored by Abid Manzoor and last updated in April 2026, includes results from proliferation assays, gene expression analysis, and transcriptomic profiling under heat and cold stress. It is shared under a CC-BY-4.0 license.
Nagaland, India, was the site of a 12-month longitudinal field study assessing a heterologous goatpox vaccine in Mithun (Bos frontalis). The dataset includes humoral response data from ELISA and virus neutralization tests, as well as cytokine marker data from serum and PBMC mRNA profiling. It was authored by Gundallahalli Bayyappa Manjunatha Reddy and last updated in April 2026.
26 synthesized quinine derivatives were evaluated for cytotoxicity against CEM and Jurkat leukemia cell lines and non-cancerous fibroblasts. Compound 22 showed the highest potency and selectivity (CC50 = 2.25 ± 0.03 µM; SCI = 4.5) and was identified as a PIM-1 kinase inhibitor. The dataset, authored by Viviana Donoso-Bustamante and last updated in April 2026, contains mechanistic study results including apoptosis induction via mitochondrial depolarization.
Supplementary Material 1 from the study 'Identification of transcription factors regulating starch biosynthesis in maize through integrated GWAS and transcriptomic analysis'. The dataset includes 10 tables with data on kernel starch content for 341 inbred lines, GWAS-associated SNPs and genes, gene expression levels, and identified transcription factors. It was authored by Jienan Han and last updated on 2026-04-21.
Primary human fibroblastic reticular cell lines from three donors were treated with or without 10ng/ml interferon-gamma for four days and analyzed via bulk RNA sequencing. The dataset is a 28.0 MB CSV file published by Zoe Chua on figshare under a CC-BY-4.0 license. It was last updated on May 19, 2026.
Between 12 August and 15 September 2008, the R.V. Solander collected underwater video and still images from 122 stations on the Carnarvon Shelf. The survey was conducted by Geoscience Australia in collaboration with the Australian Institute of Marine Science as part of the CERF Marine Biodiversity Hub's Surrogates Program. The objective was to gather co-located physical and biological data to test parameters as surrogates for benthic biodiversity patterns.
Public Accounts of Canada Table 4a provides a recapitulation of external revenues by source for each ministry and department. The dataset reconciles ministerial revenues with consolidated statements, including reconciling items like revenues from specified purpose accounts and Crown corporations. Data is published annually by the Receiver General of Canada, with the most recent update processed on 2026-04-09.
Public Services and Procurement Canada publishes this dataset, which reconciles total ministerial net expenditures with total external expenses reported in the Public Accounts of Canada. The data includes reconciling items such as consolidated specified purpose accounts, accrual adjustments, Crown corporation expenses, tax credits, and internal eliminations. It is updated annually and sourced from Volume II of the Public Accounts.
A systematic review synthesizing evidence on R-loops, epigenetic regulation, and genome stability. The review, following PRISMA guidelines, analyzed 1290 articles from PubMed and ScienceDirect up to January 2026, with 71 studies meeting inclusion criteria. It was authored by Zi Hao Jiang and last updated in April 2026.