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DNA/RNA sequences, gene expression, protein structures, metagenomics, single-cell sequencing
23,804 datasets
250 accessions of Aegilops tauschii were screened for Wheat streak mosaic virus tolerance in greenhouse trials at Kansas State University. Whole-genome sequencing data provided high-density SNP markers for association mapping, conducted by Laxman Adhikari. This repository includes SNP matrices and analysis codes for phylogenetic tree construction, PCA, and phenotypic and genotypic data analyses.
Integrated single-cell and bulk RNA sequencing data from Steroidogenic Factor-1 (SF-1) lineage Pituitary Neuroendocrine Tumors (PitNETs). The dataset was uploaded by Changxi Han to figshare and last updated on 2026-04-22. It identifies a proliferative tumor subgroup characterized by high expression of the gene RGS4.
An integrated analysis of single-cell and bulk RNA sequencing data from Steroidogenic Factor-1 (SF-1) lineage Pituitary Neuroendocrine Tumors (PitNETs). The dataset, created by Changxi Han and last updated in April 2026, identifies a tumor subgroup characterized by high expression of the RGS4 gene and its role in promoting proliferation via p53 destabilization.
Changxi Han published integrated single-cell and bulk RNA sequencing data from Steroidogenic Factor-1 (SF-1) lineage Pituitary Neuroendocrine Tumors (PitNETs) on figshare in April 2026. The 1.8 MB dataset under a CC-BY-4.0 license was used to identify a proliferative tumor subgroup driven by RGS4 expression. The analysis links RGS4 to p53 destabilization and tumor cell proliferation.
Changxi Han published a dataset on figshare in April 2026, analyzing Steroidogenic Factor-1 (SF-1) lineage Pituitary Neuroendocrine Tumors (PitNETs). The 418.9 KB XLSX file contains results from an integrated analysis of single-cell and bulk RNA sequencing data, identifying a proliferative subgroup characterized by high RGS4 expression. The dataset supports the conclusion that RGS4 promotes tumor proliferation by destabilizing p53.
An integrated analysis of single-cell and bulk RNA sequencing data from Steroidogenic Factor-1 (SF-1) lineage Pituitary Neuroendocrine Tumors (PitNETs) identifies a high-RGS4 expression subgroup linked to proliferation. The 2.6 MB Excel file, authored by Changxi Han and last updated in April 2026, contains results from functional experiments demonstrating RGS4's role in promoting tumor cell growth via p53 destabilization. This dataset is shared under a CC-BY-4.0 license on figshare.
A 12.7 KB Excel file from figshare, last updated in April 2026, presents integrated single-cell and bulk RNA sequencing analysis of SF-1 lineage Pituitary Neuroendocrine Tumors (PitNETs). The dataset, authored by Changxi Han, identifies a proliferative tumor subgroup characterized by high expression of the gene RGS4. It includes results from functional experiments showing RGS4's role in promoting tumor cell proliferation via p53 destabilization.
A 2026 research article by Helena Costa-Verdera, published on figshare under a CC-BY-4.0 license, details immune responses to retinal gene therapy. The 6.1 MB PDF describes transcriptomic and functional assay data from porcine and mice models treated with the AAV2.7m8 vector. The work identifies markers like MCP-1, IP-10, and complement C3a, and explores the role of integrins in inflammation.
Meilin Zhang published a dataset on figshare in April 2026 investigating the YKT6 gene's role in breast cancer. The data, derived from public datasets, clinic samples, and tissue microarrays, links YKT6 overexpression to poor prognosis, advanced tumor stages, and immune cell infiltration. It is a 1.1 MB PDF file available under a CC-BY-4.0 license.
A 883.1 KB PDF authored by Sang-Eun Jung and published on figshare in April 2026 details a study on ATG5-mediated autophagy in CAR-T cells. The research investigates how reinforcing inducible autophagy capacity through ATG5 overexpression helps sustain CAR-T cell function under immunosuppressive, tumor-mimicking conditions. Findings include maintained cytotoxic activity, preserved cytokine production, reduced oxidative stress in vitro, and enhanced antitumor efficacy in vivo.
12.1 KB Excel file from figshare, authored by Sang-Eun Jung and last updated in April 2026. The dataset likely contains experimental results investigating how ATG5-mediated autophagy regulation affects CAR-T cell functional durability under solid tumor stress conditions.
Yi Zhang's study presents genetic and environmental data from a case-control study of 1,566 pregnant women in Beijing, Wuhan, and Zunyi, China. The dataset includes analysis of CDKN2A/2B gene polymorphisms, haplotypes, and interactions with ozone and PM2.5 exposure related to gestational diabetes mellitus (GDM). The data was last updated on 2026-04 22 and is shared under a CC-BY-4.0 license.
Longitudinal data on the fecal microbiota of Duroc × Landrace × Yorkshire piglets, tracked from birth to day 28. The dataset, created by Bo Song and last updated in April 2026, likely contains results from 16S rRNA gene sequencing used to characterize microbial development stages and the impact of weaning. It is a small dataset at 53.5 KB.
A study investigating the anti-fatigue mechanisms of Dendrobium officinale pseudobulb extracts from different growth durations in a mouse model of chronic fatigue syndrome. The dataset includes behavioral, physiological, biochemical, and plasma metabolomics profiles from ICR mice, alongside untargeted metabolomics and HPLC analysis of the plant extracts. It was authored by Minda Zhang and last updated on 2026-04 22.
A study by Eleonora Mascheroni, last updated in April 2026, examines epigenetic and behavioral data from 48 children aged 3–36 months. The dataset includes DNA methylation levels at 13 CpG sites of the OXTR gene and parent-reported temperament scores for Surgency/Extraversion, Negative Emotionality, and Effortful Control. It compares 24 children with neurodevelopmental disabilities to 24 typically developing children.
Lonicera macranthoides genomic data includes 34 expansin and 43 aquaporin genes identified from a chromosome-level genome. Expression patterns for LmEXPA26 and LmPIP2-2 were analyzed alongside auxin-related metabolites quantified by LC–MS/MS during flower opening. The dataset was authored by Zhong Chen and uploaded to figshare in April 2026.
13 inbred mouse substrains underwent a standardized battery of behavioral assays, including open field, cocaine locomotor response, fear conditioning, prepulse inhibition, and forced swim tests. The dataset, authored by Celine L. St. Pierre and last updated in April 2026, documents significant substrain-specific differences across all measured behaviors.
A study by Qiongqiong Li applied whole-genome sequencing to characterize microbial populations across a sterile vaccine production line. The dataset, last updated in April 2026, integrates SNP-based phylogeny, sampling location metadata, and ARG/virulence profiling to identify five dominant opportunistic species and reconstruct contamination chains.
Qiongqiong Li's dataset, published on figshare in April 2026, contains genomic analysis results from a study of microbial contamination in pharmaceutical cleanrooms. It likely includes data on five dominant opportunistic species, their phylogenetic relationships, and profiles of antibiotic resistance and virulence factors. The dataset is structured as an Excel file with a size of 11.6 KB.
A 10.5 KB dataset from a study applying whole-genome sequencing to characterize microbial populations in a sterile vaccine production line. The data, authored by Qiongqiong Li and last updated on 2026-04-15, integrates SNP-based phylogeny, sampling location metadata, and ARG/virulence profiling for five dominant opportunistic species.